Invitrogen™ SON Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554814

Catalog No. PIPA554814

Description

Immunogen sequence: TEVAIESTPM ILESSIMSSH VMKGINLSSG DQNLAPEIGM QEIALHSGEE PHAEEHLKGD FYESEHGINI DLNINNHLIA KEMEHNTVCA AGTSPVGEIG EEKILPTSET KQRTVLDTYP GVSEADAGET LSSTGP Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 60%.

The protein encoded by this gene binds to a specific DNA sequence upstream of the upstream regulatory sequence of the core promoter and second enhancer of human hepatitis B virus (HBV). Through this binding, it represses HBV core promoter activity, transcription of HBV genes, and production of HBV virions. The protein shows sequence similarities with other DNA-binding structural proteins such as gallin, oncoproteins of the MYC family, and the oncoprotein MOS. It may also be involved in protecting cells from apoptosis and in pre-mRNA splicing. Several transcript variants encoding different isoforms have been described for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq].

Specifications

• Antigen: SON
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SON
• Gene Alias: 2900011L12Rik; AA409051; AU067731; BASS1; Bax antagonist selected in Saccharomyces 1; C21orf50; C81487; DBP5; DBP-5; HSPC310; HSPC312; KIAA1019; mKIAA1019; negative regulatory element-binding protein; NRE-binding protein; NREBP; Protein DBP-5; Protein SON; SON; Son cell proliferation protein; Son DNA binding protein; SON DNA-binding protein; SON3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6651
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P18583
• Gene Symbols: SON
• Immunogen: Recombinant protein corresponding to Human SON. Recombinant protein control fragment (Product #RP-91770).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov