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SORT1 Mouse anti-Human, Clone: OTI3H4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF813064

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.Specifications
SORT1 | |
Monoclonal | |
Unconjugated | |
SORT1 | |
Gp95, LDLCQ6, NT3, NTR3 | |
Mouse | |
Affinity Chromatography | |
RUO | |
6272 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI3H4 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q99523 | |
SORT1 | |
Human recombit protein fragment corresponding to amino acids 34-300 of human SORT1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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