SORT1 Monoclonal Antibody (OTI3H4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA813064

Catalog No. 50-168-4716

Description

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.

Specifications

• Antigen: SORT1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q99523
• Gene Symbols: SORT1
• Immunogen: Human recombit protein fragment corresponding to amino acids 34-300 of human SORT1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3H4
• Conjugate: Unconjugated
• Gene: SORT1
• Gene Alias: Gp95, LDLCQ6, NT3, NTR3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6272
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid