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Sortilin Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987202
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50-198-7202 100 μL
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Catalog No. 50-198-7202 Supplier Bioss Supplier No. BS6329R
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Description

Rabbit Polyclonal Antibody

Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). It is also required for protein transport from the Golgi apparatus to the endosomes. Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also, Sortilin acts as a receptor for neurotensin.

Specifications

Antigen Sortilin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Sort1
Gene Accession No. Q99523
Gene Alias 100 kDa NT receptor; 2900053A11Rik; AI852375; Glycoprotein 110; Glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; Neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1
Gene Symbols Sort1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Sortilin.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6272
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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