Invitrogen™ SOX10 Recombinant Rabbit Monoclonal Antibody (PDH0-05)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550753

Catalog No. FEMA550753

Description

Positive control: A375 cell lysate, B16F1 cell lysate, human malignant melanoma tissue, human breast tissue, human appendix tissue, rat cerebellum tissue, mouse brain tissue, A375, B16F1. Predicted band size: 50 kDa Subcellular Location: Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus.

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Specifications

• Antigen: SOX10
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O55170, P56693, Q04888
• Gene Symbols: SOX10
• Immunogen: Synthetic peptide within C terminal human SOX10 aa 457-466/466.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: PDH0-05
• Conjugate: Unconjugated
• Gene: SOX10
• Gene Alias: cls; cls/sox10; colorless; colourless; colourless/sox10; DOM; dominant megacolon; dominant megacolon, mouse, human homolog of; golas; gos; HMG-box transcription factor Sox10; MGC15649; PCWH; Protein SOX-21; SOX10; Sox-10; sox10 protein; sox10b; Sox21; SOX9; SRY; SRY (sex determining region Y)-box 10; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY box 10; SRY-box 10; SRY-box containing gene 10; SRY-box containing protein 10; SRY-box transcription factor 10; SRY-related HMG-box gene 10; transcription factor SOX-10; Transcription factor SOX-M; WS2E; WS4; WS4C; zgc:100757
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20665, 29361, 6663
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid