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Sox17 Mouse anti-Human, Clone: OTI5G6, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF500282

Encompass_Preferred

Catalog No. 50-165-9399


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5′-AACAAT-′3 or 5′-AACAAAG-3′. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17are known to cause a severe defects in fetal hematopoiesis.
Specifications

Specifications

Sox17
Monoclonal
Unconjugated
SOX17
VUR3
Mouse
Affinity Chromatography
RUO
64321
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI5G6
PBS with 8% trehalose and no preservative; pH 7.3
Q9H6I2
SOX17
Recombit protein expressed in E.coli corresponding to amino acids 177-414 of human SOX17
100 μg
Primary
Human
Antibody
IgG1
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