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SOX17 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA523382
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100 μg
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Catalog No. Quantity
PIPA523382 100 μg
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Catalog No. PIPA523382 Supplier Thermo Scientific Supplier No. PA523382

Description

Rabbit Polyclonal Antibody

SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX17
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene SOX17
Gene Accession No. Q61473, Q9H6I2
Gene Alias HMG transcription factor SOX17; HMG-box transcription factor Sox17; Sox17; Sox-17; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box 17; SRY-box containing gene 17; SRY-box transcription factor 17; SRY-related HMG-box transcription factor SOX17; transcription factor SOX-17; transcription factor SOX-17; LOW QUALITY PROTEIN: transcription factor SOX-17; VUR3
Gene Symbols SOX17
Host Species Rabbit
Immunogen A portion of amino acids 120-170 of human SOX17
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100154087, 20671, 428534, 64321
Target Species Chicken, Human, Marsupial, Mouse, Non-human Primate, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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