SOX17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-4608	150 μL

Catalog No. 50-173-4608 Supplier Proteintech Group Inc Supplier No. 249031AP150UL

Description

Rabbit Polyclonal Antibody

SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5′-AACAAT-′3 or 5′-AACAAAG-3′. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17are known to cause a severe defects in fetal hematopoiesis.

Specifications

• Antigen: SOX17
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.32 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: SOX17
• Gene Accession No.: Q61473, Q9H6I2
• Gene Alias: SOX17, Transcription factor SOX 17
• Gene Symbols: Sox17
• Host Species: Rabbit
• Immunogen: SOX17 Fusion Protein Ag19157
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20671, 312936, 64321
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG