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Invitrogen™ SOX2 Polyclonal Antibody
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Catalog No. PIPA585143
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100 μL
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PIPA585143 100 μL
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Catalog No. PIPA585143 Supplier Invitrogen™ Supplier No. PA585143
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (92%), Rat (92%), Zebrafish (87%), Japanese Medaka (87%), Xenopus laevis (85%), Cat (96%), Pig (97%), Chicken (93%), Sheep (97%), Rhesus Monkey (98%), Bovine (97%). Positive Control: NT2D1, A431, Human ESC, GL261. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX2
Applications Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene SOX2
Gene Accession No. P48431, P48432
Gene Alias ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
Gene Symbols SOX2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SOX2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20674, 6657
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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