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Invitrogen™ SOX2 Recombinant Rabbit Monoclonal Antibody (PO00-28)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA550695
Description
Positive control: Human cervical carcinoma tissue, human glioma tissue, human esophagus tissue, human tonsil tissue, human lung carcinoma tissue, human trachea tissue, F9 cell lysates, F9, mouse brain tissue, mouse lung tissue, rat brain tissue, rat hippocampus tissue. Predicted band size: 34 kDa Subcellular Location: Nucleus.
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
Specifications
SOX2 | |
Recombinant Monoclonal | |
1 mg/mL | |
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
P48431, P48432 | |
SOX2 | |
Recombinant protein within human SOX2 aa 1-317/317. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
PO00-28 | |
Unconjugated | |
SOX2 | |
ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389 | |
Rabbit | |
Protein A | |
RUO | |
20674, 499593, 6657 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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