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Invitrogen™ SOX21 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA547505
Description
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) SOX1, rhSOX2 and rhSOX15 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
The SOX gene family is defined by the Sry-related HMG box domain that mediates sequence-specific DNA binding. A variety of functions are associated with the SOX proteins during development. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. SOX21 may play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can cause an up-regulation of the OPRM1 distal promoter in mor-expressing neuronal cells.
Specifications
SOX21 | |
Polyclonal | |
Unconjugated | |
Sox21 | |
DNA-binding protein SOX21; HMG-box protein SOX21; Sox21; Sox25; SOX25SOX-A; SOXA; SOX-A; SRY (sex determining region Y)-box 21; SRY box 21; SRY-box 21; SRY-box containing gene 21; transcription factor SOX-21 | |
Goat | |
Antigen affinity chromatography | |
RUO | |
11166 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot, Immunocytochemistry | |
0.2 mg/mL | |
PBS with 5% trehalose and No Preservative | |
Q9Y651 | |
Sox21 | |
E. coli-derived recombinant human SOX21 Ser2-Leu276 (Gly102Ser). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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