Invitrogen™ SOX4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541442

Catalog No. PIPA541442

Description

Peptide sequence: STASTGGKAD DPSWCKTPSG HIKRPMNAFM VWSQIERRKI MEQSPDMHNA Sequence homology: Cow: 100%; Dog: 100%; Goat: 91%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of SOX genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 SOX genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Specifications

• Antigen: SOX4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOX4
• Gene Alias: AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20677, 6659
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q06831, Q06945
• Gene Symbols: SOX4
• Immunogen: Synthetic peptide directed towards the N-terminal of human SOX4 (aa 38-87).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG