Invitrogen™ SOX4a Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143431

Catalog No. PIPA5143431

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial. Positive control: whole zebrafish, zebrafish eye, zebrafish brain.

SOX genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of SOX genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 SOX genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Specifications

• Antigen: SOX4a
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: AA682046; ecotropic viral integration site 16; EVI16; SOX4; Sox-4; SRY (sex determining region Y)-box 4; SRY box 4; SRY-box 4; SRY-box containing gene 4; SRY-box transcription factor 4; SRY-related HMG-box gene 4; transcription factor SOX-4
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of zebrafish Sox4a. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% Proclin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG