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Invitrogen™ SOX6 Polyclonal Antibody
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Catalog No. PIPA599416
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100 μL
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PIPA599416 100 μL
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Catalog No. PIPA599416 Supplier Invitrogen™ Supplier No. PA599416
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SOX6.

The SOX6 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, which are known to play vital roles in the regulation of developmental processes and cell fate determination. SOX6, along with its close relatives SOX5 and SOX13, constitutes the SOXD subfamily, which is involved in the regulation of the development of the central nervous system, skeletal system, and cartilage. It functions by binding to specific DNA sequences and modulating the expression of target genes necessary for these developmental processes. SOX6 has been implicated in various functions, such as promoting cartilage formation by acting in conjunction with SOX9 to drive chondrogenesis. In adult neural stem cells, SOX6 is essential for the activation of radial glial-like cells and the generation of new neurons, emphasizing its role in both embryonic development and adult tissue maintenance. The dysregulation of SOX6 has been associated with developmental disorders and its potential involvement in pathologies like cancer, where it influences cell differentiation and proliferation pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX6
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SOX6
Gene Accession No. P35712, P40645
Gene Alias AI987981; HSSOX6; SOX6; Sox-6; SOXD; SOX-LZ; SRY (sex determining region Y)-box 6; SRY box 6; SRY-box 6; SRY-box containing gene 6; transcription factor SOX-6
Gene Symbols SOX6
Host Species Rabbit
Immunogen A synthesized peptide derived from human SOX6(Accession P35712), corresponding to amino acid residues S3-S53.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20679, 293165, 55553
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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