Invitrogen™ SOX8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566194

Catalog No. PIPA566194

Description

Immunogen sequence: PRRRKSAKAGH SDSDSGAELG PHPGGGAVYK AEAGLGDGHH HGDHTGQTH Highest antigen sequence identity to the following orthologs - mouse 73%, rat 70%.

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Specifications

• Antigen: SOX8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOX8
• Gene Alias: SOX8; Sox-8; SRY (sex determining region Y)-box 8; SRY box 8; SRY-box 8; SRY-box containing gene 8; transcription factor SOX-8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30812
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P57073
• Gene Symbols: SOX8
• Immunogen: Recombinant Human SOX8. Recombinant protein control fragment (Product #RP-106880).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov