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SOX9 Mouse anti-Human, Clone: OTI5G4, lyophilized, TrueMAB™
SDP

Catalog No. 501666026
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100 μg
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Catalog No. Quantity
50-166-6026 100 μg
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Catalog No. 50-166-6026 Supplier OriGene Supplier No. CF802491
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintece of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.

Specifications

Antigen SOX9
Applications Western Blot
Classification Monoclonal
Clone OTI5G4
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene SOX9
Gene Accession No. P48436
Gene Alias CMD1, CMPD1, SRA1, SRXX2, SRXY10
Gene Symbols SOX9
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-205 of human SOX9 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6662
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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