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Invitrogen™ SP1 Monoclonal Antibody (1326CT463.109.176)
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Catalog No. PIMA537649
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400 μL
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PIMA537649 400 μL
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Catalog No. PIMA537649 Supplier Invitrogen™ Supplier No. MA537649
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Mouse Monoclonal Antibody

SP1 Monoclonal Antibody for Western Blot, ICC/IF, Flow

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SP1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1326CT463.109.176
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene SP1
Gene Accession No. P08047
Gene Alias 1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Gene Symbols SP1
Host Species Mouse
Immunogen Recombinant protein from the human SP1.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6667
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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WARNING: Cancer - www.P65Warnings.ca.gov
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