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SP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA595583
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Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
|0.2mg sodium phosphate with 0.9MG NaCl, 0.9MG NaCl, 4MG trehalose, 4MG trehalose and 0.05MG sodium azide, 0.05MG sodium azide|
|O89090, P08047, Q01714|
|E.coli-derived human SP1 recombit protein (Position: Q384-A603).|
|Human, Mouse, Rat|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Transcription factor Sp1; SP1; TSFP1|
|20683, 24790, 6667|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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