SP1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA595583

Catalog No. PIPA595583

Description

Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Specifications

• Antigen: SP1
• Classification: Polyclonal
• Formulation: 0.2mg sodium phosphate with 0.9MG NaCl, 0.9MG NaCl, 4MG trehalose, 4MG trehalose and 0.05MG sodium azide, 0.05MG sodium azide
• Gene Accession No.: O89090, P08047, Q01714
• Gene Symbols: SP1
• Immunogen: E.coli-derived human SP1 recombit protein (Position: Q384-A603).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: SP1
• Gene Alias: Transcription factor Sp1; SP1; TSFP1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20683, 24790, 6667
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized