Invitrogen™ SP100 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553476

Catalog No. PIPA553476

Description

Immunogen sequence: QARTHHNQAS DIIVISSEDS EGSTDVDEPL EVFISAPRSE PVINNDNPLE SNDEKEGQEA TCSRPQIVPE PMDFRKLSTF RESFKKRVIG QDHDFSESSE Highest antigen sequence identity to the following orthologs: Mouse - 24%, Rat - 26%.

This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

Specifications

• Antigen: SP100
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SP100
• Gene Alias: A430075G10Rik; DKFZp686E07254; FLJ00340; FLJ34579; lysp100b; nuclear antigen Sp100; nuclear autoantigen Sp-100; Nuclear dot-associated Sp100 protein; SP 100; SP100; SP100 nuclear antigen; SP100-HMG nuclear autoantigen; speckled 100 kDa
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6672
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23497
• Gene Symbols: SP100
• Immunogen: Recombinant protein corresponding to Human SP100. Recombinant protein control fragment (Product #RP-91589).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov