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Invitrogen™ SPACA1 Polyclonal Antibody
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Catalog No. PIPA560314
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100 μL
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Catalog No. Quantity
PIPA560314 100 μL
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Catalog No. PIPA560314 Supplier Invitrogen™ Supplier No. PA560314
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRQDQQSIIL VNDSAILEVR KESHPLAFEC DTLDNNEIVA TIKFTVYTSS ELQMRRSSLP A Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 69%.

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPACA1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SPACA1
Gene Accession No. Q9HBV2
Gene Alias 1700124L11Rik; 4930540L03Rik; RGD1560284; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; sperm acrosome associated 1; sperm acrosome membrane-associated protein 1
Gene Symbols SPACA1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SPACA1. Recombinant protein control fragment (Product #RP-102938).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 81833
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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