SPAG6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7996	150 μL

Catalog No. 50-172-7996 Supplier Proteintech Group Inc Supplier No. 124621AP150UL

Description

Rabbit Polyclonal Antibody

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintece of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Specifications

• Antigen: SPAG6
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: SPAG6
• Gene Accession No.: O75602, Q9JLI7
• Gene Alias: pf16, Protein PF16 homolog, Repro SA 1, SPAG6, sperm associated antigen 6, Sperm flagellar protein
• Gene Symbols: Spag6
• Host Species: Rabbit
• Immunogen: SPAG6 Fusion Protein Ag3130
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 360747, 381350, 9576
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG