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Invitrogen™ SPAG8 Polyclonal Antibody
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Catalog No. PIPA531948
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100 μL
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PIPA531948 100 μL
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Catalog No. PIPA531948 Supplier Invitrogen™ Supplier No. PA531948
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, U87-MG, MCF-7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPAG8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene SPAG8
Gene Accession No. Q99932
Gene Alias BS-84; CILD28; CT142; HSD-1; hSMP-1; MH-SPAG8; SMP1; SMP-1; SPAG3; Spag8; sperm associated antigen 8; sperm associated antigen 8-like protein; sperm membrane protein 1; Sperm membrane protein BS-84; sperm-associated antigen 8; testicular tissue protein Li 177
Gene Symbols SPAG8
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SPAG8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26206
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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