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Invitrogen™ SPAG8 Polyclonal Antibody
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Catalog No. PA550264
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100 μL
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Catalog No. Quantity
PA550264 100 μL
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Catalog No. PA550264 Supplier Invitrogen™ Supplier No. PA550264
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total SPAG8 protein.

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPAG8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene SPAG8
Gene Accession No. Q99932
Gene Alias BS-84; CILD28; CT142; HSD-1; hSMP-1; MH-SPAG8; SMP1; SMP-1; SPAG3; Spag8; sperm associated antigen 8; sperm associated antigen 8-like protein; sperm membrane protein 1; Sperm membrane protein BS-84; sperm-associated antigen 8; testicular tissue protein Li 177
Gene Symbols SPAG8
Host Species Rabbit
Immunogen Fusion protein corresponding to a region derived from internal residues of human sperm associated antigen 8.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26206
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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