Invitrogen™ SPAG8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550264

Catalog No. PA550264

Description

The antibody detects endogenous levels of total SPAG8 protein.

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Specifications

• Antigen: SPAG8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPAG8
• Gene Alias: BS-84; CILD28; CT142; HSD-1; hSMP-1; MH-SPAG8; SMP1; SMP-1; SPAG3; Spag8; sperm associated antigen 8; sperm associated antigen 8-like protein; sperm membrane protein 1; Sperm membrane protein BS-84; sperm-associated antigen 8; testicular tissue protein Li 177
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26206
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q99932
• Gene Symbols: SPAG8
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human sperm associated antigen 8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG