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Invitrogen™ SPANXB1 Polyclonal Antibody
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Catalog No. PIPA545150
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100 μL
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PIPA545150 100 μL
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Catalog No. PIPA545150 Supplier Invitrogen™ Supplier No. PA545150
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Description

Rabbit Polyclonal Antibody

Peptide sequence: MPETPTGDSD PQPAPKKMKT SESSTILVVR YRRNVKRTSP EELVNDHARE Sequence homology: Human: 100%.

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-tail orientation with SPANX family member B2, which appears to be a duplication of the B1 locus. The SPANXB genes are unique members of this gene family, since they contain an additional 18 nt in their coding region compared to the majority of family members. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPANXB1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SPANXB1
Gene Accession No. Q9NS25
Gene Alias B1; cancer/testis antigen 11.2; cancer/testis antigen family 11, member 2; CT11.2; Nuclear-associated protein SPAN-Xb; nuclear-associated protein SPAN-Xf; SPANX family member B/F; SPANX family member B1; SPANX family member F1; SPANX family, member B1; SPANX family, member B2; SPANX family, member F1; SPANX family, member F2; SPANXB; SPANX-B; SPANXB1; SPANXB2; SPANXF1; SPANXF2; sperm protein associated with the nucleus on the X chromosome B/F; sperm protein associated with the nucleus on the X chromosome B1; sperm protein associated with the nucleus, X chromosome, family member B1
Gene Symbols SPANXB1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human SPANXB1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728695
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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