Invitrogen™ SPARC Monoclonal Antibody (5031)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA143027

Catalog No. MA143027

Description

MA1-43027 detects SPARC in human, rat and bovine samples. MA1-43027 has successfully been used in radioimmunoassays, Western blot, ELISA and immunohistochemistry applications. MA1-43027 was derived from human platelet osteonectin.

SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SPARC
• Classification: Monoclonal
• Concentration: 9.7 mg/mL
• Formulation: 50% water with 50% glycerol and no preservative
• Gene Accession No.: P09486, P13213, P16975
• Gene Symbols: SPARC
• Immunogen: Human osteonectin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry, Radioimmune Assays (RIA), Western Blot
• Clone: 5031
• Conjugate: Unconjugated
• Gene: SPARC
• Gene Alias: Basement membrane protein 40; basement-membrane protein 40; BM40; BM-40; Cysteine rich protein; OI17; ON; Osteonectin; osteonectin precursor; Secreted acidic cystein rich glycoprotein; secreted acidic cysteine rich glycoprotein; Secreted acidic cystein-rich glycoprotein (osteonectin); secreted protein acidic and cysteine rich; secreted protein acidic and rich in cysteine; Secreted protein acidic and rich in cysteine (SPARC); secreted protein, acidic, cysteine-rich (osteonectin); secreted protein, acidic, cysteine-rich [osteonectin]; SPARC
• Host Species: Mouse
• Purification Method: SDS-PAGE
• Regulatory Status: RUO
• Gene ID (Entrez): 24791, 282077, 6678
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid