Invitrogen™ SPARC Polyclonal Antibody

Catalog No.	Quantity
PIPA595441	100 μg

Catalog No. PIPA595441 Supplier Invitrogen™ Supplier No. PA595441

Description

Rabbit Polyclonal Antibody

Human SPARC shares 97% amino acid (aa) sequence identity with both mouse and rat SPARC. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human HUVEC whole cell, human placenta tissue, human A375 whole cell, human U20S whole cell, human U87 whole cell, rat testis tissue, rat kidney tissue, mouse testis tissue, mouse kidney tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: SPARC
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene: SPARC
• Gene Accession No.: P07214, P09486, P16975
• Gene Alias: Basement membrane protein 40; basement-membrane protein 40; BM40; BM-40; Cysteine rich protein; OI17; ON; Osteonectin; osteonectin precursor; Secreted acidic cystein rich glycoprotein; secreted acidic cysteine rich glycoprotein; Secreted acidic cystein-rich glycoprotein (osteonectin); secreted protein acidic and cysteine rich; secreted protein acidic and rich in cysteine; Secreted protein acidic and rich in cysteine (SPARC); secreted protein, acidic, cysteine-rich (osteonectin); secreted protein, acidic, cysteine-rich [osteonectin]; SPARC
• Gene Symbols: SPARC
• Host Species: Rabbit
• Immunogen: E.coli-derived human SPARC recombinant protein (Position: E107-I303).
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20692, 24791, 6678
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG