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Invitrogen™ SPARC Recombinant Rabbit Monoclonal Antibody (PD00-57)
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Catalog No. FEMA550724
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100 μL
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Catalog No. Quantity
FEMA550724 100 μL
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Catalog No. FEMA550724 Supplier Invitrogen™ Supplier No. MA550724
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Human malignant melanoma tissue, human glioma tissue. Predicted band size: 35 kDa Subcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane.

SPARC gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPARC
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone PD00-57
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene SPARC
Gene Accession No. P09486
Gene Alias Basement membrane protein 40; basement-membrane protein 40; BM40; BM-40; Cysteine rich protein; OI17; ON; Osteonectin; osteonectin precursor; Secreted acidic cystein rich glycoprotein; secreted acidic cysteine rich glycoprotein; Secreted acidic cystein-rich glycoprotein (osteonectin); secreted protein acidic and cysteine rich; secreted protein acidic and rich in cysteine; Secreted protein acidic and rich in cysteine (SPARC); secreted protein, acidic, cysteine-rich (osteonectin); secreted protein, acidic, cysteine-rich [osteonectin]; SPARC
Gene Symbols SPARC
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6678
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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