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Invitrogen™ Spastin Polyclonal Antibody
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Catalog No. PIPA597226
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100 μL
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PIPA597226 100 μL
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Catalog No. PIPA597226 Supplier Invitrogen™ Supplier No. PA597226
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HKQAFEYISI ALRIDEDEKA GQKEQAVEWY KKGIEELEKG IAVIVTGQGE QCERARRLQA KMMTNLVMAK DRLQLLEKMQ PVLPFSKSQT DVYNDSTNLA CRNGHLQSES GAVPKRKDPL THTSNSLPRS KTVMKTGSAG LSGHHRAPSY SGLSMVSGVK QGSGPAPTTH KGTPKTNRTN KPSTPTTATR KKKDLKNFRN VDSNLA; Positive Samples: Mouse heart; Cellular Location: Cytoplasm, Endoplasmic reticulum, Endosome, Membrane, Nucleus, Single-pass membrane protein, centrosome, cytoskeleton, microtubule organizing center, perinuclear region, spindle.

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Spastin
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.03 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SPAST
Gene Accession No. Q9UBP0
Gene Alias ADPSP; ATPase; fidgetin-like 1; FSP2; HAMAP-Rule:MF_03021}; hypothetical protein zgc:85952; Kiaa1083; KIAA183; LOW QUALITY PROTEIN: spastin; mKIAA1083; si:ch73-233a22.3; SPAST; spastic paraplegia 4 (autosomal dominant; spastic paraplegia 4 (autosomal dominant; spastin); spastic paraplegia 4 homolog; spastic paraplegia 4 protein; Spastin; spastin {ECO:0000255; SPG4; zgc:85952
Gene Symbols SPAST
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 120-325 of human SPAST (NP_0557612).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6683
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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