Invitrogen™ Spastin Recombinant Rabbit Monoclonal Antibody (RM346)

Catalog No.	Quantity
PIMA527980	100 μL

Catalog No. PIMA527980 Supplier Invitrogen™ Supplier No. MA527980

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.

Specifications

• Antigen: Spastin
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: RM346
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene: SPAST
• Gene Accession No.: Q9UBP0
• Gene Alias: ADPSP; ATPase; fidgetin-like 1; FSP2; HAMAP-Rule:MF_03021}; hypothetical protein zgc:85952; Kiaa1083; KIAA183; LOW QUALITY PROTEIN: spastin; mKIAA1083; si:ch73-233a22.3; SPAST; spastic paraplegia 4 (autosomal dominant; spastic paraplegia 4 (autosomal dominant; spastin); spastic paraplegia 4 homolog; spastic paraplegia 4 protein; Spastin; spastin {ECO:0000255; SPG4; zgc:85952
• Gene Symbols: SPAST
• Host Species: Rabbit
• Immunogen: A peptide corresponding to the N-terminus of human Spastin.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6683
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG