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Invitrogen™ SPATA13 Polyclonal Antibody
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Catalog No. PIPA559096
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100 μL
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PIPA559096 100 μL
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Catalog No. PIPA559096 Supplier Invitrogen™ Supplier No. PA559096
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Rabbit Polyclonal Antibody

Immunogen sequence: ALRPAEWGTL DGSDLEDTDD AFQRSTHRSR SLRRAYGLGR ICLLDAPQNH ATPTIATGQV PAVCEILVRD PENNSMGYRR SKSTDNLAFL KKSSFKRKST SNLADLRTAH Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 54%.

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPATA13
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Spata13
Gene Accession No. Q96N96
Gene Alias adenomatous polyposis coli stimulated exchange factor 2; APC-stimulated guanine nucleotide exchange factor 2; ARHGEF29; ASEF2; C79050; ESTM11; mFLJ00298; Spata13; spermatogenesis associated 13; spermatogenesis-associated protein 13; spt13; X83327
Gene Symbols Spata13
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SPATA13. Recombinant protein control fragment (Product #RP-98018).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221178
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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