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Tocris Bioscience™ Spautin 1
GSA_VAGREENER_CHOICE

Catalog No. 519710
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51-971-0 10 mg
51-975-0 50 mg
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Description

USP10 and USP13 inhibitor; inhibits autophagy

Spautin 1 is an inhibitor of autophagy; inhibits USP10 and USP13 activity (IC50 values are 0.6 and 0.7 μM respectively) and promotes degradation of Vps34 (class III PI 3-kinase) complexes. Selectively promotes apoptosis of cancer cells under starvation conditions. Prevents the PDGF-induced conversion from the contractile to synthetic phenotype in vascular smooth muscle cells.

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Specifications

Quantity 10 mg
Product Type Spautin 1
Purity >98%
Molecular Weight (g/mol) 271.26
Inhibitors Spautin 1

For Research Use Only

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