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Invitrogen™ SPC24 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA595812
Description
Immunogen sequence: MAAFRDIEEV SQGLLSLLGA NRAEAQQRRL LGRHEQVVER LLETQDGAEK QLREILTMEK EVAQSLLNAK EQVHQGGVEL QQLEAGLQEA GEEDTRLKAS LLQLTRELEE LKEIEADLER QEKEVDEDTT VTIPSAVYVA QLYHQVSKIE WDYECEPGMV KGIHHGPSVA QPIHLDSTQL SRKFISDYLW SLVDTEW; Positive Samples: Jurkat, HeLa, 293T; Cellular Location: Chromosome, Nucleus, centromere, kinetochore.
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.
Specifications
SPC24 | |
Polyclonal | |
Unconjugated | |
SPC24 | |
2410030K01Rik; AV109292; hSpc24; kinetochore protein Spc24; SPBC24; SPC24; SPC24, NDC80 kinetochore complex component; SPC24, NDC80 kinetochore complex component, homolog; SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae); spindle pole body component 24 homolog | |
Rabbit | |
Affinity Chromatography | |
RUO | |
147841, 67629 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
2.12 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
Q8NBT2, Q9D083 | |
SPC24 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SPC24 (NP_8723191). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Safety and Handling
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