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SPDYA Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988108
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50-198-8108 100 μL
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Catalog No. 50-198-8108 Supplier Bioss Supplier No. BS7901R
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Description

Rabbit Polyclonal Antibody

Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.

Specifications

Antigen SPDYA
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SPDYA
Gene Accession No. Q5MJ70
Gene Alias 4921517J08Rik; 4930548B21Rik; GS4; hSpy/Ringo A; Lm23; MGC110856; MGC57218; MLZ-465; mSpy/Ringo A; OTTHUMP00000082662; OTTHUMP00000082663; OTTHUMP00000082664; Protein expressed in male leptotene and zygotene spermatocytes 465; Rapid inducer of G2/M progression in oocytes A; RINGO A; Ringo antibody; RINGO3; RINGOA; Spdy1; Spdya; spdya {ECO:0000250; speedy A; speedy A1; speedy A2; speedy homolog 1; speedy homolog A; speedy homolog A (Xenopus laevis); Speedy protein A; speedy/ringo; speedy/RINGO cell cycle regulator family member A; Speedy-1; spermatogenesis related protein Gs4; Spy antibody; SPY1; UniProtKB:Q5MJ70}
Gene Symbols SPDYA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human SPDYA.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 245711
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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