Invitrogen™ SPDYC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558963

Catalog No. PIPA558963

Description

Immunogen sequence: SPLVTTQVEL GGCSRQGGGN GFLRFRQHQE VQAFLSLLED SFVQEFLSKD PCFQISDKY Highest antigen sequence identity to the following orthologs: Mouse - 28%, Rat - 28%.

Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correct localization of the active form of Aurora B in prometaphase.

Specifications

• Antigen: SPDYC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPDYC
• Gene Alias: hSpy/Ringo C; rapid inducer of G2/M progression in oocytes C; RINGO C; Ringo2; RINGOC; SPDYC; speedy; speedy C; speedy homolog C; speedy protein C; speedy/RINGO cell cycle regulator family member C
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 387778
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5MJ68
• Gene Symbols: SPDYC
• Immunogen: Recombinant protein corresponding to Human SPDYC. Recombinant protein control fragment (Product #RP-97558).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG