Spectinomycin DihydroChloride Pentahydrate, Cell Culture Grade, PROMO, Thermo Scientific Chemicals

Description

Spectinomycin dihydrochloride pentahydrate is the hydrochloride salt form of spectinomycin, an aminocyclitol compound showing antibacterial and antimicrobial activities.

General Description

• Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
• Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

• Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
• In the laboratory, this compound is used in cell culture applications
• It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
• It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
• In genetic approaches, this compound can be used to amplify the plasmid copy number

Specifications

Chemical Identifiers

• CAS: 22189-32-8
• Molecular Formula: C14H36Cl2N2O12
• Molecular Weight (g/mol): 495.34 g/mol
• MDL Number: MFCD00150886
• InChI Key: DCHJOVNPPSBWHK-UXXUFHFZSA-N
• Synonym: Spectinomycin dihydrochloride
• PubChem CID: 67108398
• ChEBI: CHEBI:9217
• IUPAC Name: dihydrogen (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one pentahydrate dichloride
• SMILES: [H+].[H+].O.O.O.O.O.[Cl-].[Cl-].CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O

• Type: Spectinomycin Dihydrochloride Pentahydrate
• Physical Form: Powder
• Color: White
• Quantity: 5 g
• Solubility Information: Soluble in water, methanol, dimethyl sulfoxide, ethanol and dimethyl formamide.
• Grade: Cell Culture
• Chemical Name or Material: Spectinomycin dihydrochloride pentahydrate

Safety and Handling

EINECSNumber	244-554-3
RTECSNumber	WG7400000
TSCA	No
Recommended Storage	Keep cold

RUO - Research Use Only