Invitrogen™ Spectrin alpha-1 Recombinant Rabbit Monoclonal Antibody (1U5K4)

Spectrin alpha-1 Recombinant Rabbit Monoclonal Antibody (ARC1650)

Supplier:  Invitrogen™ MA535815

Catalog No. PIMA535815

Description

Spectrin alpha-1 Recombinant Monoclonal Antibody for Western Blot

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: Spectrin alpha-1
• Classification: Recombinant Monoclonal
• Concentration: 1.05 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P02549, P08032
• Gene Symbols: SPTA1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 2300-2400 of human alpha 1 Spectrin (P02549).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 1U5K4
• Conjugate: Unconjugated
• Gene: SPTA1
• Gene Alias: 2610027H02Rik; A2a; AF093576; a--fodrin; AI451697; alpha II spectrin; alpha-fodrin; alpha-I spectrin; alpha-II spectrin; alpha-spectrin 1, erythroid; alpha-spectrin 2; alpha-spectrin 2, brain; brain alpha-spectrin; EIEE5; EL2; elliptocytosis 2; erythroid alpha-spectrin; erythroid spectrin alpha; fodrin alpha chain; ha; hemolytic anemia; HPP; HS3; ihj; inhibitory protein factor; IPF; mutant alpha spectrin; NEAS; neuroscience mutagenesis facility, 4; nmf4; noerythroid alpha-spectrin 2; nonerythroid alpha-spectrin 2; spectrin alpha 1; spectrin alpha chain, brain; spectrin alpha chain, erythrocyte; spectrin alpha chain, erythrocytic 1; Spectrin alpha chain, non-erythrocytic 1; spectrin alpha, erythrocytic 1; spectrin alpha, non-erythrocytic 1; spectrin, alpha, erythrocytic 1; spectrin, alpha, erythrocytic 1 (elliptocytosis 2); spectrin, alpha, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit; sph; SPH3; spherocytosis; Spna1; Spna-1; Spna2; Spna-2; SPTA; Spta1; SPTA2; SPTAN1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20739, 289257, 6708
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid