Invitrogen™ Spectrin beta-4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121581

Catalog No. PIPA5121581

Description

Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart. Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier.

Specifications

• Antigen: Spectrin beta-4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPTBN4
• Gene Alias: 1700022P15Rik; 5830426A08Rik; beta-IV spectrin; beta-spectrin 4; dyn; EMBL BAB83243.1; KIAA1642; lnd; lumbosacral neuroaxonal dystrophy; neuroaxonal dystrophy; nmf261; nmf379; quivering; qv; ROSA62; SpbIV; spectrin beta 4; spectrin beta chain, brain 3; spectrin beta chain, non-erythrocytic 4; spectrin beta, non-erythrocytic 4; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain 3; SPNB4; SPTBN3; SPTBN4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57731
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q9H254
• Gene Symbols: SPTBN4
• Immunogen: Lys64-Ser285 (Accession Q9H254), with N-terminal His Tag.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG