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Invitrogen™ Spectrin beta-4 Polyclonal Antibody
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Catalog No. PIPA562972
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100 μL
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PIPA562972 100 μL
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Catalog No. PIPA562972 Supplier Invitrogen™ Supplier No. PA562972
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AWEERFSSLR RLTTIEKIKA EQSKQPPTPL LGRKFFGDPT ELAAKAAPLL RPGGYERGLE PLARRASDTL SAEVRTRVGY VRQELKPERL QPRIDRLP Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart. Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Spectrin beta-4
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SPTBN4
Gene Accession No. Q9H254
Gene Alias 1700022P15Rik; 5830426A08Rik; beta-IV spectrin; beta-spectrin 4; dyn; EMBL BAB83243.1; KIAA1642; lnd; lumbosacral neuroaxonal dystrophy; neuroaxonal dystrophy; nmf261; nmf379; quivering; qv; ROSA62; SpbIV; spectrin beta 4; spectrin beta chain, brain 3; spectrin beta chain, non-erythrocytic 4; spectrin beta, non-erythrocytic 4; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain 3; SPNB4; SPTBN3; SPTBN4
Gene Symbols SPTBN4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Spectrin beta-4. Recombinant protein control fragment (Product #RP-104041).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57731
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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