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Invitrogen™ SPG20 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5110421
Description
Immunogen sequence: MEQEPQNGEP AEIKIIREAY KKAFLFVNKG LNTDELGQKE EAKNYYKQGI GHLLRGISIS SKESEHTGPG WESARQMQQK MKETLQNVRT RLEILEKGLA TSLQNDLQEV PKLYPEFPPK DMCEKLPEPQ SFSSAPQHAE VNGNTSTPSA GAVAAPASLS LPSQSCPAEA PPAYTPQAAE GHYTVSYGTD SGEFSSVGEE FYRNHSQPPP LETLGLDADE LILIPNGVQI FFVNPAGEVS APSYPGYLRI VRFLDNSLDT VLNRPPGFLQ VCDWLYPLVP DRSPVLKCTA GAYMFPDTML QAAGCFVGVV LSSELPEDDR ELFEDLLRQM SDLRLQANWN RAEEENEFQI.
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
Specifications
SPG20 | |
Polyclonal | |
Unconjugated | |
SPART | |
AI840044; C79168; KIAA0610; mKIAA0610; Spart; Spartin; Spartin-like protein; spastic paraplegia 20 (Troyer syndrome); spastic paraplegia 20 (Troyer syndrome) homolog; Spastic paraplegia 20 protein; spastic paraplegia 20, spartin (Troyer syndrome) homolog; spastic paraplegia 20, spartin (Troyer syndrome) homolog (human); SPG20; TAHCCP1; Trans-activated by hepatitis C virus core protein 1 | |
Rabbit | |
Affinity chromatography | |
RUO | |
229285, 23111, 295053 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.74 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q8N0X7, Q8R1X6 | |
SPART, Spg20 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human SPG20 (NP_055902.1). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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