Invitrogen™ SPG21 Monoclonal Antibody (2B11)

Catalog No.	Quantity
PIMA521907	100 μg

Catalog No. PIMA521907 Supplier Invitrogen™ Supplier No. MA521907

Description

Mouse Monoclonal Antibody

Peptide Sequence: PHKIRDIPVT IMDVFDQSAL STEAKEEMYK LYPNARRAHL KTGGNFPYLC RSAEVNLYVQ IHLLQFHGTK YAAIDPSMVS AEELEVQKGS LGISQE.

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: SPG21
• Applications: ELISA
• Classification: Monoclonal
• Clone: 2B11
• Concentration: 0.2-1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: SPG21
• Gene Accession No.: Q9NZD8
• Gene Alias: acid cluster protein 33; ACP33; BM-019; C78576; D9Wsu18e; GL010; Maspardin; MAST; spastic paraplegia 21 (autosomal recessive, Mast syndrome); Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog; spastic paraplegia 21 homolog (human); Spastic paraplegia 21 protein; SPG21
• Gene Symbols: SPG21
• Host Species: Mouse
• Immunogen: SPG21 (NP_057714, 211 a.a. ~ 306 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51324
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ