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Invitrogen™ SPG21 Polyclonal Antibody
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Catalog No. PIPA559176
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100 μL
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PIPA559176 100 μL
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Catalog No. PIPA559176 Supplier Invitrogen™ Supplier No. PA559176
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Rabbit Polyclonal Antibody

Immunogen sequence: AEYTHKSPRV HSLILCNSFS DTSIFNQTWT ANSFWLMPAF MLKKIVLGNF SSGPVDPMMA DAIDFMVDRL ESLGQSELAS RLT Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPG21
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SPG21
Gene Accession No. Q9NZD8
Gene Alias acid cluster protein 33; ACP33; BM-019; C78576; D9Wsu18e; GL010; Maspardin; MAST; spastic paraplegia 21 (autosomal recessive, Mast syndrome); Spastic paraplegia 21 autosomal recessive Mast syndrome protein; Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog; spastic paraplegia 21 homolog (human); Spastic paraplegia 21 protein; SPG21
Gene Symbols SPG21
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SPG21. Recombinant protein control fragment (Product #RP-98038).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51324
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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