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SPHK1 Mouse anti-Human, Clone: OTI1A6, liquid, TrueMAB™
SDP

Catalog No. 501677010
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100 μL
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50-167-7010 100 μL
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Catalog No. 50-167-7010 Supplier OriGene Supplier No. TA507215
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Mouse Monoclonal Antibody

SPHK1 (Sphingosine Kinase 1) catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Specifications

Antigen SPHK1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1A6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene SPHK1
Gene Accession No. Q9NYA1
Gene Alias SPHK
Gene Symbols SPHK1
Host Species Mouse
Immunogen Full length human recombit protein of human SPHK1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8877
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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