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Invitrogen™ SPIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551065

Catalog No. PA551065


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Description

Description

SPIN1 Polyclonal Antibody detects endogenous levels of SPIN1 protein.

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SPIN1
Polyclonal
Unconjugated
SPIN1
30000 Mr metaphase complex; OCR; Ovarian cancer-related protein; SPIN; Spin1; spindlin 1; Spindlin1; spindlin-1; SSEC P; TDRD24
Rabbit
Antigen Affinity Chromatography
RUO
10927, 20729, 361217
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q4V8J7, Q61142, Q9Y657
SPIN1
Synthesized peptide derived from the Internal region of human Spindlin-1 (aa 111-160).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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