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Invitrogen™ SPIN1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA551065
Description
SPIN1 Polyclonal Antibody detects endogenous levels of SPIN1 protein.
SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
Specifications
SPIN1 | |
Polyclonal | |
Unconjugated | |
SPIN1 | |
30000 Mr metaphase complex; OCR; Ovarian cancer-related protein; SPIN; Spin1; spindlin 1; Spindlin1; spindlin-1; SSEC P; TDRD24 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
10927, 20729, 361217 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q4V8J7, Q61142, Q9Y657 | |
SPIN1 | |
Synthesized peptide derived from the Internal region of human Spindlin-1 (aa 111-160). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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