Invitrogen™ SPIN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551065

Catalog No. PA551065

Description

SPIN1 Polyclonal Antibody detects endogenous levels of SPIN1 protein.

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Specifications

• Antigen: SPIN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPIN1
• Gene Alias: 30000 Mr metaphase complex; OCR; Ovarian cancer-related protein; SPIN; Spin1; spindlin 1; Spindlin1; spindlin-1; SSEC P; TDRD24
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10927, 20729, 361217
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q4V8J7, Q61142, Q9Y657
• Gene Symbols: SPIN1
• Immunogen: Synthesized peptide derived from the Internal region of human Spindlin-1 (aa 111-160).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG