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Invitrogen™ Spinesin Polyclonal Antibody
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Catalog No. PIPA518013
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100 μg
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Catalog No. Quantity
PIPA518013 100 μg
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Catalog No. PIPA518013 Supplier Invitrogen™ Supplier No. PA518013
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Spinesin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene TMPRSS5
Gene Accession No. Q9H3S3
Gene Alias adrenal mitochondrial protease; Amp; MGC141886; MGC148044; Spinesin; Tmprss5; Transmembrane protease serine 5; transmembrane protease, serine 5; transmembrane protease, serine 5 (spinesin)
Gene Symbols TMPRSS5
Host Species Goat
Immunogen Synthetic peptide sequence (LDWIHDTAQDSLL) corresponding to the C-terminus amino acids of TMPRSS5 (aa 445-457).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80975
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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