Invitrogen™ SPINK6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550127

Catalog No. PA550127

Description

The antibody detects endogenous levels of total SPINK6 protein.

SPINK6 (serine peptidase inhibitor, Kazal type 6), also known as BUSI2, is an 80 amino acid secreted protein that contains one kazal-like domain and is thought to function as a serine protease inhibitor. The gene encoding SPINK6 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also associated with chromosome 5 and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute mye-logenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: SPINK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPINK6
• Gene Alias: acrosin inhibitor; BUSI2; EG433180; Kallikrein inhibitor; Kazal type serine protease inhibitor 1; protease inhibitor H; serine peptidase inhibitor, Kazal type 6; serine protease inhibitor Kazal-type 6; Spink5l1; Spink6; UNQ844; UNQ844/PRO1782
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 404203
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6UWN8
• Gene Symbols: SPINK6
• Immunogen: Synthesized peptide derived from internal of human SPINK6 (aa 13-62).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG