Invitrogen™ SPINK6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552779

Catalog No. PIPA552779

Description

Immunogen sequence: VDCGEFQDTK VYCTRESNPH CGSDGQTYGN KCAFCKAIVK SGGKISLKH Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 78%.

SPINK6 (serine peptidase inhibitor, Kazal type 6), also known as BUSI2, is an 80 amino acid secreted protein that contains one kazal-like domain and is thought to function as a serine protease inhibitor. The gene encoding SPINK6 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also associated with chromosome 5 and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute mye-logenous leukemias and myelodysplastic syndrome.

Specifications

• Antigen: SPINK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPINK6
• Gene Alias: acrosin inhibitor; BUSI2; EG433180; Kallikrein inhibitor; Kazal type serine protease inhibitor 1; protease inhibitor H; serine peptidase inhibitor, Kazal type 6; serine protease inhibitor Kazal-type 6; Spink5l1; Spink6; UNQ844; UNQ844/PRO1782
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 404203
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6UWN8
• Gene Symbols: SPINK6
• Immunogen: Recombinant protein corresponding to Human SPINK6. Recombinant protein control fragment (Product #RP-90497).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG