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Invitrogen™ SPINLW1 Polyclonal Antibody
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Catalog No. PA550656
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100 μL
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PA550656 100 μL
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Catalog No. PA550656 Supplier Invitrogen™ Supplier No. PA550656
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total EPPIN protein.

Eppin, an epididymal protease inhibitor, belongs to the WFDC family and to the telomeric cluster. The gene encoding the protein is localized to chromosome 20q12-q13 in centromeric and telomeric clusters. It expresses three mRNAs encoding two isoforms of a cystine-rich protein that contains Kunitz-type and WAP-type (four disulfide core) protease inhibitor consensus sequences. The mouse gene lies in a cluster of putative Eppin-like genes on mouse chromosome 2. Following ejaculation, Eppin is bound to semenogelin in seminal plasma and on human spermatozoa. This complex of Eppin and Semenogelin can provide antimicrobial activity for spermatozoa. It can also provide for the preparation and survival of spermatozoa for fertility in the female reproductive tract. Eppin, which is a secreted protein, is expressed in epididymis and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPINLW1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene EPPIN
Gene Accession No. O95925, Q9DA01
Gene Alias 1700024E17Rik; cancer/testis antigen 71; cancer/testis antigen 72; CT71; CT72; dJ461P17.2; epididymal peptidase inhibitor; epididymal protease inhibitor; EPPIN; EPPIN1; EPPIN2; EPPIN3; protease inhibitor WAP7; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); Spinlw1; WAP four-disulfide core domain protein 7; WAP four-disulfide core domain protein 8; WAP7; WFDC7; Wfdc8
Gene Symbols EPPIN
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57119, 75526
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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