Invitrogen™ SPIRE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559362

Catalog No. PIPA559362

Description

Immunogen sequence: LQRGESSMRS EKPSTAHHRP LRSIARFSSK SKSMDKSDEE LQFPKELMED WSTMEVCVDC KKFISEIISS SRRSLVLANK RARLKRKTQ Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.

Specifications

• Antigen: SPIRE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPIRE1
• Gene Alias: KIAA1135; Protein spire homolog 1; SPIR1; Spir-1; spire actin nucleation factor 1; spire family actin nucleation factor 1; spire homolog 1; spire type actin nucleation factor 1; SPIRE1; spire-type actin nucleation factor 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56907
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q08AE8
• Gene Symbols: SPIRE1
• Immunogen: Recombinant protein corresponding to Human SPIRE1. Recombinant protein control fragment (Product #RP-98282).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov