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Invitrogen™ SPO11 Polyclonal Antibody
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Catalog No. PIPA530549
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100 μL
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PIPA530549 100 μL
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Catalog No. PIPA530549 Supplier Invitrogen™ Supplier No. PA530549
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (83%), Rat (85%), Pig (91%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPO11
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene SPO11
Gene Accession No. Q9Y5K1
Gene Alias AI449549; Cancer/testis antigen 35; CT35; hypothetical protein LOC402982; meiotic recombination protein SPO11; MGC39953; SPATA43; spermatogenesis associated 43; SPO11; SPO11 initiator of meiotic double stranded breaks; SPO11 meiotic protein covalently bound to DSB; SPO11 meiotic protein covalently bound to DSB homolog; SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae); SPO11, initiator of meiotic double stranded breaks; sporulation protein, meiosis-specific, SPO11 homolog; sporulation protein, meiosis-specific, SPO11 homolog (S. cervisiae); TOPVIA; zgc:77876
Gene Symbols SPO11
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SPO11. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23626
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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